Europe's secondary competition is reaching its conclusion with the quarter-final lie-up set to bedecided in today's draw.
Manchester United are the Premier League's sole representatives in the hat following their 2-1 aggregate win over Rostov.
With a Champions League place (and a shiny European trophy) up for grabs for the winner, the Red Devils will be hoping for an easy passage, but several European big boys await.
See the draw in full
Anderlecht v Manchester United
United have a little history with Anderlecht – the sides have met six times in European competition, with United winning four and losing two. Their last meeting, in October 2000, saw the Brussels club win 2-1 – a result that helped them pip their opponents to top spot in their Champions League group. A more positive omen for United is that their record win in any competition came against Anderlecht– a 10-0 triumph way back in the 1956 European Cup.
Celta Vigo v Genk
Celta, the only hope for Spain to continue their recent dominance of this competition, face Genk.
Ajax v Schalke
Two former winners of the UEFA Cup – Ajax in 1992, Schalke in 1997 – are drawn together.
Lyon v Besiktas
A tricky round trip for Lyon, second favourites for the trophy behind United.